Journal of Reproductive Health and Contraception

RELATIONSHIP OF 25-HYDROXY-VITAMIN D3 SERUM LEVELS WITH CYCLOOXYGENASE-2 IN ADENOMIOSIS PATIENTS

Adenomyosis is a condition in which endometrium is ectopically placed in the myometrium. The most frequent symptoms of adenomyosis is chronic pelvic pain. Pain is a sensoric stimuli that can be affected by COX-2. Some studies found that 25-Hidroxy-Vitamin D₃ serum level has the ability to affect COX-2 serum level and modulate pain sensation. The aim of this study is to analyze correlation between 25-Hidroxy-Vitamin D₃ and COX-2 serum level in patient with adenomyosis. This was an analytical observational study. Subjects were women diagnosed with adenomyosis who met the study criteria (n = 35). Their 25-Hidroxy-Vitamin D₃ and COX-2 serum level were measured

Romulya A. I, Rachmawaty A. , Azis M. A.