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Rectal Irrigation with Colostrum for Treatment of Meconium Disease

Meconium related gastrointestinal abnormalities could be seen from the Meconium Plug Syndrome (MPS) and Meconium Disease (MD). Considering the causes of neonatal intestinal obstruction, MD is usually seen in low birth weight neonates and characterized by abdominal distension and vomiting despite spontaneous meconium passage in few days of life at most cases. Diagnosis and treatment can be utilized by contrast enemas. Surgical treatment is very rare and is applied in case of failure of enema administration or perforation. In this case study, an extremely low birth weight neonate with meconium disease and intestinal perforation who managed successfully by peritoneal lavage and rectal irrigation with colostrum is being reported. In this report we suggested that colostrum can be used in treatment of MD or MPS, alternatively to other enemas. In addition, further investigations are needed for determining the laxative feature of colostrum’s in such conditions.


Nesrin C*, Nihat D, Erdal P, Burhan B, Kemal A, Oguz T, Murat D and Kaan D

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